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It is important to note that this concern is entirely theoretical -- no oncological adverse effects have been reported in the limited preclinical studies -- but the biological plausibility is high enough to warrant serious consideration

Judk P, Esposito S, Coppieters G, Van Eenoo P, Deventer K

As an adhesion molecule, CD11a can facilitate the recruitment and entry of T cells into the synovial tissue via LFA-1(CD11a/CD18)/intercellular cell adhesion molecule (ICAM)-1 pathway (139)

Xie T, Bai Z, Chen Z, Liang H, Liu T, Lam LK, et al

You can collect the bones in a bag and store them in your freezer until you are ready to cook them

Due to the specificity of each sample, it's hard to forecast and depend on sample preparation as well as analytical characteristics