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Emerging data suggest that GLP-1 RAs may influence aging biology in other organ systems such as the brain, cardiovascular system, and kidneys via effects on inflammation, oxidative stress, and cellular senescence 7,26

Epidemiology 20 , 512522 (2009)

For insulin tolerance testing (ITT), mice were fasted on aspen bedding for 6 h and 0.75 U kg 1 insulin was administered by i.p

Naltrexone and bupropion (Contrave) This medication helps reduce appetite and cravings

consequently, this may represent a potential concern during GLP-1 RA-based obesity interventions

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