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Vitamin B12 is an essential water-soluble vitamin that plays an important role in many functions in the body

Atherosclerosis progression, as a chronic inflammatory mechanism, is characterized by immune system dysregulation associated with increased pro-inflammatory cytokine production, including interleukin 6 (IL-6), tumor necrosis factor- (TNF-), and IL-1, as well as pattern recognition receptor proteins like CRP (170, 261267)

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In the combination study with semaglutide (CagriSema), adding the amylin axis to the GLP-1 axis produced greater body-weight reduction than either molecule alone