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The data suggested that release of the cysteine moiety of GSH is critical for the restoration of transcriptional response to cystine starvation, which corroborated the signaling result of p-GCN, p-eIF2 and notably ATF4, which induces the expression of genes containing AARE (Fig

Current studies demonstrate that LPS exerts multidimensional pathological effects on the heart, including calcium dysregulation, neurohumoral imbalance, oxidative stress, autophagy impairment, and cross-activation of signaling pathways

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doi: 10.1007/s13668-023-00451-6 102 BarreaLVerdeLCamajaniECerneaSFrias-ToralELamabadusuriyaDet al