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Research strongly suggests yes

[53] Hepatic enzyme inducers such as phenytoin, carbamazepine, and rifampin may increase the metabolism of prednisone, potentially reducing its therapeutic efficacy

Without FDA oversight, theres a greater risk of contamination

If you dont have a therapist or are looking for a new therapist, the Substance Abuse and Mental Health Services Administration (SAMHSA) has an online directory of qualified providers, or you can call 1-800-662-4357

Ketogenic diets for body weight loss: a comparison with other diets