PMID: 10543018
Al-Aly explained that the use of GLP-1s has soared in the last couple years while multiple studies have captured their far-reaching benefits, but [we] realized that no one has comprehensively investigated the effectiveness and risks of GLP-1 receptor agonists across all possible health outcomes. In the study, Al-Aly and colleagues mapped out associations between GLP-1s and 175 possible health outcomes by comparing a cohort of people with diabetes who used the treatments (n = 215,970) with: those who used sulfonylureas (n = 159,465)
The benefits of weight loss go beyond improving glycemic control, including reducing cardiovascular risk factors, and improving health-related quality of life and common obesity-related comorbidities of T2D, such as osteoarthritis and sleep apnea [47]
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GLP-1s, or GLP-1 receptor agonists, are medications that mimic the action of the naturally occurring hormone glucagon-like peptide-1 and occupy its receptors
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