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Spine immobility from fibrosis and ossification is a major complication Vision damaging eye inflammation can also occur Fracture of fused spine can lead to damage to the spinal cord Stiffness of the spine and chest wall can make breathing difficult Inflammation of aorta or major artery coming from heart Inflammation of the kidney is rare Early heart disease due to chronic inflammation leading to heart attacks can occur in ankylosing spondylitis Early and effective therapy can prevent most of these complications

Recommended for individuals with absorption issues and severe deficiencies, B12 injections are considered more effective because they bypass the digestive tract and deliver the vitamin directly into the bloodstream

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The LR3 version stays active longer, potentially helping injured tissues heal more completely

Its a synthetic version of B12 that is often preferred due to its stability and cost-effectiveness

Neurology 63 (1), 3339