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GPX5 does not contain selenium cysteine (Secys) at its active site, but instead uses cysteine residues (Cys) as its active site

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Roy D, Perreault M, Marette A

The primary efficacy endpoint assessed by the research team was the change from baseline in HbA1c levels following the 12 week experimental treatment period

The most common side effects reported in Phase 2 trials include nausea, diarrhea, vomiting, and constipation