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Tirzepatide has a plasma half-life of approximately 5 days (120 hours), supporting once-weekly subcutaneous dosing

GLP-1 medications (such as semaglutide, sold under brand names like Ozempic and Wegovy) have gained remarkable attention for their ability to help people shed unwanted pounds by curbing appetite and improving blood sugar balance

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Once-weekly 2.4mg semaglutide led to a 12.7 kg (~28 lb) weight loss over placebo in the pivotal Phase 3 trial (NCT03548935)

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