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Cardiometabolic benefits Both Ozempic and retatrutide have demonstrated improvements in various cardiometabolic risk factors, such as blood pressure, lipid profiles, and glycemic control

The SELECT clinical trial included over 17,600 adults aged 45 years and older with overweight or obesity and a prior history of heart disease and who did not have diabetes

Lelo et al

2022;22(Suppl 14):617

Managing emotional eating University Hospitals Sussex NHS Foundation Trust

The GLP-1 component stimulates insulin secretion in a glucose-dependent manner, suppresses inappropriate glucagon release, slows gastric emptying, and reduces appetite through central nervous system pathways