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Because these medications work in part by slowing how quickly food leaves the stomach, the most frequent GLP-1 side effects are gastrointestinal symptoms, such as: Nausea Vomiting Diarrhea Constipation Upset stomach or heartburn These symptoms are usually most pronounced during the first few weeks of treatment or after a dose increase

Straining during bowel movements puts pressure on the veins in the rectum, causing them to swell

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Here is the complete dosage chart for 5mg/mL concentration: Some people need doses between these standard steps

In this case, the concentration depends on how much water you add, which gives you control over the final concentration