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The mitochondrion is the cell's energy-generating furnace

Acetyl-L-carnitine improves pain, nerve regeneration, and vibratory perception in patients with chronic diabetic neuropathy: An analysis of two randomized, placebo-controlled trials

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The review highlights FOXO4-DRI's unique mechanism as a peptide-based senolytic with high selectivity for senescent cells, while noting challenges for clinical translation including peptide delivery and stability