These drugs were chosen because they represent different modes of action: paclitaxel and vincristine are microtubule-targeting agents, cisplatin forms covalent bonds with DNA and by that causes intra-strand and inter-strand cross-links that interfere with DNA replication and transcription, and doxorubicin intercalates into DNA and inhibiting topoisomerase II
doi: 10.1016/j.semcdb.2018.04.016 20 WittMReutterK
These criteria help identify patients who may benefit most from medical intervention rather than lifestyle changes alone
Entendiendo al consumidor GLP1 La era del GLP1 ha dado lugar a varios tipos de consumidores distintos, cada uno con necesidades nutrimentales compartidas, pero tambin matizadas: Consumidores que actualmente usan terapias GLP1, enfrentan desafos nicos, como supresin del apetito, lo que puede dificultar cubrir sus requerimientos nutrimentales
Trends Cancer 5 , 558568 (2019)
Both undernutrition and obesity can disrupt this axis