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It was done by one of the UK medical schools

In rare cases, they can cause more serious side effects such as: Pancreatitis (inflammation of the pancreas) Hypoglycemia (low blood sugar) Kidney problems Gallbladder problems Allergic reactions Patients should seek immediate medical attention if they experience symptoms such as severe abdominal pain, persistent nausea or vomiting, rapid heartbeat, difficulty breathing, or swelling of the face, lips, tongue, or throat

In some circles this route has been regarded as an effective alternative to parenteral administration since the 1950s, during which time several studies showed serum vitamin B12 concentration to normalise after taking large oral doses

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Persistent, spreading, or blistering reactions are a signal to stop entirely and seek professional evaluation, since these may indicate a true allergy rather than ordinary transient irritation

Skin Rash from Vitamin B12 Injections Skin rashes are a common side effect and usually show up as small red bumps or irritated patches