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It accounts for more than 56,000 emergency room visits, 2,600 hospitalizations, and an estimated 500 deaths per year due to acute liver failure

The researchers believe svL4 serves as a substrate for transglutaminases (TGMs), enabling cross-linking of structural proteins to reconstruct a functional stratum corneum

Since PS-expressing eryptotic erythrocytes are cleared by efferocytosis, this mechanism might elicit immunogenic effects as well

Van den Dobbelsteen DJ, Nobel CS, Schlegel J, Cotgreave IA, Orrenius S, Slater AF

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