doi: 10.1038/nrgastro.2017.109 8 EstesCRazaviHLoombaRYounossiZSanyalAJ
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Pataer A, He Y, Correa AM, Fang B, Roth JA, Wistuba II, Swisher SG
These results are significantly outperforming older anti-obesity medications, which typically produced 5-8% weight loss
Furthermore, the REWIND trial demonstrated a 12% reduction in major adverse cardiovascular events (MACE) ( p = 0.026), including among patients without established cardiovascular disease, alongside renoprotective effects evidenced by reductions in albuminuria [56]