10.1016/j.mce.2015.02.017 17 SodhiM.RezaeianzadehR.KezouhA.EtminanM
Wensley had no interest in quitting an effective drug
A 2020 meta-analysis published in The BMJ (k=129 studies, N=10,069,955) found that prediabetes was associated with a 15% increased risk of all-cause mortality, a 13% increased risk of cardiovascular disease, and a 16% increased risk of stroke compared with normoglycemia [13]
For us to consider medication-driven obesity treatments as equivalent to bariatric surgery, it's essential that they demonstrate mortality benefits across all obesity patients, including those who do not have cardiovascular disease or diabetes
Compounded GLP-1s come with their own risks
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