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This preservative action is what allows a reconstituted vial to be used multiple times over several weeks without becoming contaminated.

Key Takeaways No standard combination dose is established for routine patient use

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One of the RCTs found significant mean improvements in Clinical Global Impressions-Improvement (CGI-I) score and cellular methylation capacity, but not in the Aberrant Behaviour Checklist (ABC), Social Responsiveness Scale (SRS) or GSH metabolism, with those who had the lowest methionine status at baseline (suggesting impaired methylation capacity) significantly more likely to respond to supplementation

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