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B12 injections have no risk for overdose because excess vitamin B12 is just excreted in the urine

Simultaneous determination of purpurin, munjistin and mollugin in rat plasma by ultra high performance liquid chromatography-tandem mass spectrometry: application to a pharmacokinetic study after oral administration of Rubia cordifolia L

PLoS ONE 7 , e36935 (2012)

For reproducibility this means the Certificate of Analysis should make the form explicit and be matched to the lot, with identity confirmed by mass spectrometry

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