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The neuroprotective effects of GLP-1R agonists may be closely related to their impact on insulin resistance and glucose metabolism

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Overall, the study found that rats treated with GHRP-6 experienced a complete prevention of heart failure and decreased mortality rate among the rats

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188 These findings suggest that CTSB inhibitors may act on both acinar cells and macrophage-driven inflammation and that dual-targeted strategies focusing on CTSB and its downstream signaling (e.g., NF-B) may offer a more comprehensive approach to treatment