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If you have severe or intolerable side effects such as nausea, vomiting, diarrhea, constipation, worsening of fatigue, and dizziness, your healthcare provider will pause the medication for a few weeks and keep you on the previous tolerable dose
Four (4) events of hypoglycemia defined as a plasma glucose less than 54 mg/dL occurred in 2 (1.6%) of 125 SAXENDA-treated patients and 1 event occurred in 1 (0.8%) of 126 placebo-treated patients
Their website references a 6-month clinical trial of 180 participants taking semaglutide or tirzepatide alongside the WW Clinic programme (Heinberg et al.)
doi: 10.1146/annurev.phyto.40.021102.150133 63 Ramirez-PradoJ