Gastrointestinal Side Effects When Consuming Excess Sugar Eating large quantities of sugar while on semaglutide frequently triggers nausea, bloating, and abdominal discomfortnot because the medication fails, but because your altered digestive capacity struggles to process high volumes of simple carbohydrates efficiently
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doi: 10.1007/s00011-016-0967-5 62 XiangXMaHChenYZhangDMaSWangHet al
DOI: Published online: October 15, 2025 1 Diabetes Care Center, Jinnouchi Hospital, Kumamoto, Japan 2 Division of Endocrinology and Metabolism, Department of Internal Medicine, Kurume University School of Medicine, Kurume, Japan 3 Kurinami Clinic, Kanzaki, Kumamoto, Japan 4 Division of Cardiovascular Medicine, Diabetes Care Center, Jinnouchi Hospital, Kumamoto, Japan 5 Division of Preventive Cardiology, Department of Cardiovascular Medicine, Kumamoto University Hospital, Kumamoto, Japan Corresponding author: Hideaki Jinnouchi
By restoring the intestinal barrier, L-Glutamine helps prevent these inappropriate immune reactions, potentially reducing the frequency and severity of food-triggered symptom flares
As an added benefit, participants in the study also shed an average of 6.4 pounds