The future of weight loss drugs market Wegovy and Zepbound have set a high bar, showing 10-20% weight loss and a whole host of clinical benefits
Given its potential in controlling blood sugar levels, Receptor Grade IGF-1 LR3 may reduce insulin levels and the need for exogenous insulin in diabetes
For instance, a study published in The New England Journal of Medicine found that individuals taking semaglutide lost an average of 14.9% of their body weight over 68 weeks, compared to just 2.4% in the placebo group
The evidence base, however, is narrow and almost entirely preclinical
however, data that support such evidence are limited
We also examined the expression of genes involved in fatty acid synthesis: ACC, PGC-1, PGC-1, C/EBP, FAS, PGC1, and SREBP-1c