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GIP receptor activation further supports energy balance by enhancing nutrient utilization and improving metabolic efficiency

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Improved wound healing, reduced inflammation, reduced hepatic fat content, decreased infarct size following myocardial infarction or intracranial stroke, improved vascular function with decreased oxidative stress, improved endothelial dysfunction, and lowering of albuminuria have also been observed in pre-clinical studies [24]

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For the latest on Phase 3 TRIUMPH trial progress, see our Retatrutide 2026 Phase 3 Update

17: 225-235 Fernandez C, Proto C (1992): L-carnitine in the treatment of chronic myocardial ischemia