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It also has a tyrosine residue to replace the first amino acid at the N-terminus, which researchers consider to help increase the stability of the peptide

This clinical study with NAD+ IV infusion demonstrates improved depression and anxiety symptoms in 50 individuals with cravings and addictive behaviors.

References Chang, C

In these cases, a maintenance injection is often needed every 2-3 months to keep levels stable, as the body cant consistently source it otherwise

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The 2017 Drug Testing and Analysis SAR review compiled the broader peptidic GH secretagogue class within which both compounds sit (PMID 26811125)