The drug is metabolized via proteolytic cleavage and beta-oxidation of the fatty acid side chain, with metabolites excreted primarily in urine and feces
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Other combination formulations include tirzepatide with glycine , tirzepatide with niacinamide , and the triple compound of tirzepatide with glycine and B12 , each designed to address specific nutritional needs during treatment
[118] The tentative approval means that a scientific assessment of the generic drug was completed successfully, and that contracts and supply chains can be established, but that selling the drug would depend on intellectual property constraints