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Anti-Inflammatory Effects Lowers inflammation markers, reducing chronic pain It may be beneficial for autoimmune conditions Helps in conditions like arthritis, tendonitis, and muscle strain 5

For example, progesterone inhibited NF-B signaling and reduced NO and IL-12 production in LPS-stimulated murine bone marrow-derived and alveolar macrophages, respectively (129132)

It has been associated with autoimmune diseases such as multiple sclerosis, autoimmune thyroiditis, systemic lupus erythematous, oral lichen planus, rheumatoid arthritis, autoimmune hepatitis and Sjgrens syndrome ( Journal of Oral and Maxillofacial Pathology , Sep-Dec., 2015)

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