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Nrf2 plays a major role in the cellular defense system by controlling xenobiotic and oxidative stress conditions by controlling the expression of antioxidants and detoxifying genes in normal cells (Tonelli et al., 2018)
Other medications with effects on sodium channels, such as gabapentinoids and baclofen, are also commonly used, though there is inconsistent evidence on the efficacy of gabapentin for cramps in ALS [181]
Aging Pathobiology and Therapeutics
Depression and risk for Alzheimer disease: systematic review, meta-analysis, and metaregression analysis
Incidence and clinical characteristics of inflammatory bowel disease in a developed region of Guangdong Province, China: A prospective population-based study
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