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Two-tailed paired t-test (ns: not significant, p = 0.2213)
Furthermore, liraglutide enhances the susceptibility of gemcitabine-resistant pancreatic cancer cells to apoptosis by downregulating ATP-binding cassette transporter G2 (ABCG2) via NF-B signaling [75]
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What was initially presented as a 50% relative reduction and an absolute 7 per 100 person benefit for fewer hospitalizations at the half-way interim analysis point turned out to be ~30% relative and only 3 per 100 absolute reduction
While semaglutide is safe for most individuals, some may experience side effects
This could be attributed to long-acting GLP-1RA being more effective than short-acting GLP-1RA in regard to glycaemic and weight control, as shown by a systematic review including 14 trials [29]
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