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The result showed that daily oral administration of 300 mg of lipoic acid for three months prevented the deterioration of contrast sensitivity in patients with diabetes and improved it in healthy patients compared to placebo (84)

[45] High level of IGF1 in acromegaly is related to an increased risk of some cancers, particularly colon cancer and thyroid cancer

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Consistent with previous reports 31 , BHB had a similar effect on CD8 + T cells (Extended Data Fig

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These findings motivated human use but have not been replicated in powered human RCTs