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Looking ahead, in the first quarter of 2020 revenues were up 5% driven by HIV product sales of $4.1 billion, up 14% thanks to continued uptake of Biktarvy with $1.7 billion in sales, and the companys CAR-T cancer therapy Yescarta, which generated $140 million in sales in the quarter compared to $96 million in 1Q19

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Consistent weekly weight loss of 1-2 pounds per week becomes common after week 6 as appetite control combines with caloric deficit to create sustained fat loss

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Reduced protein intake, a common consequence of appetite suppression, particularly in older adults or those with low baseline muscle mass, further predisposes to loss of lean tissue [30]

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For patients with significant baseline B12 depletion or documented absorption issues, methylcobalamin (the natural form) or cyanocobalamin (the synthetic form) injectionstypically 1,000 mcg monthlyprovide more direct delivery and bypass the compromised absorption pathway

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