Ive been seeing the same thing, especially in my psychiatric patients
However, sustained palpitations, chest pain, or fainting require immediate medical evaluation
The American Gastroenterological Association's 2022 clinical practice guideline on obesity pharmacotherapy, published in Gastroenterology, states: "We suggest using semaglutide 2.4 mg subcutaneous weekly for adults with obesity or overweight with weight-related comorbidities (conditional recommendation, moderate-certainty evidence)." This guideline also notes that pharmacotherapy should accompany, not replace, lifestyle intervention
SCFAs: The Microbial Molecules That Tell the Brain to Stop Eating SCFAs like butyrate, propionate, and acetate: activate GLP-1 reduce cravings stabilize energy support insulin sensitivity balance blood sugar regulate appetite hormones Reference Butyrate & Appetite Hormone Regulation (Scientific Reports, 2019) Low SCFAs = hunger dysregulation
This prevents accidental transfer to other people or pets
Patients who have pre-diabetes are at a higher risk of developing type 2 diabetes, which is one of the most common complications of obesity