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doi:10.1096/fj.202000605RR 22

Obesity is a chronic medical condition, similar to high blood pressure or high cholesterol, that often requires ongoing treatment

Following this, Banting signed a contract with Connaught Laboratories of the University of Toronto for the large-scale production of their insulin extract which they used to successfully treat a further six patients

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Data search PubMed searches were performed using relevant terms, including GLP-1, GLP-1 receptor agonists, Exenatide BID, Lixisenatide, Liraglutide, Albiglutide, Dulaglutide, Exenatide LAR, heart rate, and pulse rate

This is a potential issue for all PET tracers targeting receptors or other saturable systems, but especially for highly potent binders