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This improvement in exercise capacity can lead to more effective workouts, which in turn can contribute to increased fat loss and muscle gain over time

Some early studies in animals have shown a potential risk to foetal development, which is why current advice is to avoid use in pregnancy and stop treatment well in advance of trying to conceive

However, broader guidance from NICE, the NHS, and the MHRA provides a clear framework for understanding how unapproved substances should be approached

Kraemer WJ, Volek JS, French DN, Rubin MR, Sharman MJ, Gomez AL, Ratamess NA, Newton RU, Jemiolo B, Craig BW, et al

Exposures and Outcomes Exposures to the index medication were identified from outpatient dispensing records, where medication classes were defined by National Drug Codes based on Anatomical Therapeutic Chemical (ATC)-defined medication classes (ESM Table S2)