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GHK-Cu plays an important role in tissue regeneration, wound healing, and skin remodeling through multiple mechanisms: it promotes the recruitment and activation of repair cells, enhances the synthesis of extracellular matrix components (including collagen, elastin, and glycosaminoglycans), modulates extracellular matrix turnover by increasing both metalloproteinases and their inhibitors, and exhibits powerful anti-inflammatory and antioxidant effects

First, Wegovy is a brand-name biologic with no generic equivalent

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Some debate exists about long-term use since obesity tends to be chronic, these medications likely need to be continued to maintain weight loss (as stopping leads to regain, based on observations)

Conversely, elevated GDF8 (myostatin) exacerbates muscle loss and metabolic dysfunction, presenting a therapeutic target for obesity-related sarcopenia (Hittel et al