Treatment depends on the underlying cause
These are normal metabolic adaptation events, not medication failure
First, Alzheimers disease and other dementias are strongly linked to metabolic dysfunctionespecially insulin resistance in the brain, sometimes labeled type 3 diabetes. Second, a class of diabetes and weight-management medicines called GLP-1 receptor agonists (GLP-1 RAs) shows early but increasingly consistent signals that they may lower dementia risk in people with type 2 diabetes, and possibly slow specific biological changes of Alzheimers in small clinical trials
Free Radical Biology and Medicine, 39, 34554
Red meat and the associated metabolites, such as trimethylamine-N-oxide (TMAO) [2], are gaining attention, not only for individual health but also for planetary health ( l-carnitine, the active form of dietary carnitine and a driver of TMAO, is emerging as a target for CVD prevention and treatment, because it has an important role in the oxidation of fatty acids and cardiac energy metabolism [3]
You could try Wegovy, Mounjaro or Saxenda first