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Diabetic Retinopathy Progression Some clinical trials have reported worsening diabetic retinopathy in patients using semaglutide, especially among those with long-standing diabetes, elevated baseline A1C levels, or concurrent insulin therapy

Multiple sclerosis, an autoimmune demyelinating disease of the central nervous system, may benefit from the anti-inflammatory and neuroprotective properties of GLP-1RAs

Comparison of the effects of glucagon-like peptide receptor agonists and sodium-glucose cotransporter 2 inhibitors for prevention of major adverse cardiovascular and renal outcomes in type 2 diabetes mellitus

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However, nausea is primarily a semaglutide side effect, and glycine moderating influence, while helpful, may not eliminate it entirely

doi: 10.1056/nejmoa2206038