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Clinical evidence shows users lose nearly 15% of their body weight compared to just 2.4% through lifestyle modifications alone

Impact of microvascular disease on cardiovascular outcomes in type 2 diabetes: Results from the LEADER and SUSTAIN 6 clinical trials

They are choosing between a treatment available now (tirzepatide) and one that may become available in the next 12 to 18 months (CagriSema)

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Many clinicians therefore use BMI as a screening entry point rather than a verdict, supplementing it with waist circumference, metabolic laboratory values, and a fuller assessment of health status