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Unfortunately, the use of KD also has certain limitations

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Hyperthermia is a promising treatment option for several types of cancer, including non-small cell lung cancer (Wang, Lin 2013), bladder cancer (Colombo 2013

However, a larger increase in glutamate content without concomitant decrease in aspartate observed in an epileptic patient almost certainly represents increased de novo synthesis (Mangia et al., 2012)