Extended Data Figure 5 C347 6.36b F stabilizes the interaction interface between GLP-1R and NAMs
Introducing pills removes significant barriers to GLP-1 adoption, such as cost, needle discomfort, pharmacy logistics and manufacturing supply issues
Statistical significance was calculated using an unpaired, two-tailed Students t-test or ANOVA, followed by Tukeys post hoc test where appropriate, using GraphPad 9.0
Direct receptor-mediated effects This is where things get scientifically fascinating
With GLP-1 (glucagon-like peptide-1 receptor agonists) medications, there are now more options available for people looking to help manage their weight and related health conditions
Curcumin and turmerin have been recorded to inhibit glucosidase in the small intestine