Pale or jaundiced skin , often linked to megaloblastic anemia from inadequate B12
Joint discomfort associated with B12 supplementation is uncommon and not listed amongst the recognised adverse effects in the Summary of Product Characteristics (SmPC) for licensed B12 preparations or in the British National Formulary (BNF)
Like other medicine or pharmaceutical products, api-products also have some side effects or are dangerous for allergic individuals
For blood clots in the leg, compression stockings are commonly recommended
Immune Modulation at the Maternal-Fetal Interface Research has demonstrated that hCG modulates immune responses at the maternal-fetal interface through epigenetic mechanisms specifically, hCG inhibits CXCL10 expression in human endometrial stromal cells by enhancing EZH2 expression and inducing H3K27me3 histone methylation at the CXCL10 promoter, thereby suppressing T cell recruitment to the implantation site
Side effects B12 injections are generally considered safe with minimal side effects when administered appropriately