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[5] [6] The guideline emphasises a stepwise approach to treatment intensification, typically progressing from metformin monotherapy to dual therapy (often with an SGLT2 inhibitor, DPP-4 inhibitor, pioglitazone, or sulphonylurea), and then to triple therapy or insulin-based regimens

The prescription aligns with the drug's approved use

This mechanism distinguishes GLP-1 agonists from older secretagogues that could trigger insulin release regardless of glucose status

So if youre trying to lose weight with GLP-1s, its best to limit the amount of alcohol you drink, says Dr

Learn what happens if you get more B12 than necessary

It works from inside out to create visible changes