ATTAIN-1: Eli Lilly's orforglipron 36 mg achieved 12.4% loss (27.3 lbs) at 72 weeks
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This distinction matters for dosing because compounded tirzepatide arrives in multi-dose vials rather than pre-filled pens
It is important to recognize that mucus in stool can result from numerous conditions unrelated to tirzepatide therapy, including irritable bowel syndrome, inflammatory bowel disease, infections, food intolerances, and other gastrointestinal disorders
2 Propensity score matching likely isnt adequately accounting for difference in baseline diabetes severity, especially since the commentators point to a high degree of missing HbA1c values and not including other diabetes complications like nephropathy, neuropathy and peripheral vascular disease
Decreased dendritic spine density on prefrontal cortical pyramidal neurons in schizophrenia