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R., Wu, X., & Yin, J
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The American Diabetes Association (ADA) recommends insulin as the preferred agent for glycemic control during pregnancy due to its established safety profile and inability to cross the placental barrier in significant amounts
Finally, GIPr agonism may decrease the nauseating effects of GLP-1 agonism through area postrema inhibitory neurons potentially allowing for higher therapeutic doses of GLP-1 analogs with decreased adverse effects [13]
One study shows that 12 weeks of injections results in substantially lower caloric intake
66 Human clinical studies remain limited to small, non-randomized, or retrospective case series, which cannot support definitive therapeutic claims.64
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