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pointed out the involvement of vascular endothelial growth factor (VEGF) in the onset of OHSS because the serum VEGF concentration was high at the onset of OHSS in their patients case [4]

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Researchers have observed this protective effect through glutathiones activation of the Nrf2/HO-1 signaling pathway [4]

Imai H, Hirao F, Sakamoto T, Sekine K, Mizukura Y, Saito M et al (2003) Early embryonic lethality caused by targeted disruption of the mouse PHGPx gene