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Apart from lipid biosynthesis, another critical pro-inflammatory process that NADPH supports in myeloid cells is the production of cytotoxic, diffusive reactive radicals, such as reactive oxygen species (ROS) via NADPH oxidases (NOXes), as well as nitric oxide ( NO) via nitric oxide synthases (NOSes)

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Use of AI tools: Artificial Intelligence (AI) assistance (GPT-5, OpenAI) was used only for improving the English language, grammar, and phrasing of the manuscript