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N Engl J Med 387:107588

doi: 10.1089/dna.2021.0465 166 FalusAGiliczeA

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Because basal homocysteine levels may affect the increase in postmethionine-load homocysteine in patients with abnormal basal homocysteinemia, the net increase in postmethionine-load homocysteine above fasting values should be taken into account in the global assessment of CBS defects

Heres a breakdown of their relationship and differences: Alpha-Lipoic Acid (ALA)