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PMCID: PMC6271067
Phenotypic Screening Deconvolution After a phenotypic screen identifies active compounds, metabolic fingerprinting provides the first mechanistic triage layer separating compounds that act through energy metabolism, membrane disruption, nucleotide biosynthesis, or signalling pathway inhibition without requiring individual target binding assays
The Complicated Reality Behind GLP-1 Drugs Part of the confusion surrounding these medications comes from the difference between brand-name drugs and the growing market for compounded versions
Lancet 2018;392:151929.PubMed 70
The physician tells you whether the medication is right
