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doi:10.1097/JCN.0000000000000469

Despite promising mechanistic insights and preclinical data, clinical translation has faced substantial limitations and risks that restrict widespread implementation

Less muscle means a lower basal metabolic rate, which means your body burns fewer calories at rest after weight loss than it did before

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Dulaglutide Dulaglutide is another GLP- 1 synthetic analog which consists of two DPP- 4 resistant GLP- 1 molecules that are covalently linked to a modified IgG4 Fc fragment that acts as carrier, limiting the renal clearance of the molecule [93]

Research has shown improvements in blood sugar regulation and other metabolic indicators