Higher body mass dilutes the per-kilogram dose, which can reduce both the effects and side effects at lower dose levels
For example, I had a patient who was able to get her Ozempic at a fraction of the cost through Novo Nordisks assistance program after her insurance only partially covered the medication
doi: 10.1167/iovs.15-17201 152 AppleDJEscobar-GomezMZauggBKleinmannGBorkensteinAF
They're really remarkably beneficial, across multiple organ systems, he said
When a drug is in shortage, compounders may be able to prepare a compounded version of that drug if they meet certain requirements in the Federal Food, Drug, and Cosmetic (FD&C) Act
For instance, following online conversations with their USA lippy sisters, the newly registered NHS wonder jab for obesity, semaglutide (Ozempic or Wegovy), has been procured on private prescription by many UK lipoedema patients for years for its useful, off ticket side-effect of weight loss, when it was only available on NHS prescription for type 2 diabetes in the UK